Moderate associations identified for strabismus and mental health disorders – Consumer Health News
FRIDAY, March 11, 2022 (HealthDay News) — Strabismus is moderately associated with anxiety disorder, schizophrenia, bipolar disorder and depressive disorder in children, according to a study published online March 10 in JAMA Ophthalmology.
Yoon H. Lee, MD, of the University of California, Los Angeles, and colleagues conducted a cross-sectional study analyzing claims data from 12,005,189 patients enrolled in a health plan between January 1, 2007 and January 31 December 2017. Children younger than 19 at the time of strabismus diagnosis were included; controls were children in the same database with no eye disease code other than refractive error.
The researchers found that the adjusted odds ratios for the association of mental illness with strabismus were 2.01 (95% confidence interval [CI], 1.99 to 2.04), 1.83 (95% CI, 1.76 to 1.90), 1.64 (95% CI, 1.59 to 1.70), 1.61 ( 95% CI, 1.59 to 1.63) and 0.99 (95% CI, 0.97 to 1.02) for anxiety disorder, schizophrenia, bipolar disorder, depressive disorder and related disorder to substance use, respectively. A moderate association was observed between each type of strabismus and anxiety disorder, schizophrenia, bipolar disorder and depressive disorder; odds ratios ranged from 1.23 (95% CI, 1.17 to 1.29) to 2.70 (95% CI, 2.66 to 2.74) for the association between esotropia and bipolar disorder and between exotropia and anxiety disorder, respectively.
“These findings should alert ophthalmologists and optometrists to advise children and their caregivers about the risk of mental illness,” the authors write. “They should consider incorporating a screening tool for mental health issues for patients with strabismus and referring pediatric patients with strabismus for a mental health assessment.”
One author disclosed financial ties to Luminopia and Novartis.