Single black men have the worst prognosis with localized prostate cancer

This article was originally published here

Can J Urol. 2022 Feb;29(1):10992-11002.


INTRODUCTION: To determine whether marital status combined with race serve as prognostic factors for survival in localized prostate cancer.

MATERIALS AND METHODS: Patients with localized prostate cancer were retrospectively extracted from the Surveillance, Epidemiology, and End Results (SEER) database. The chi-square test was used to study the association between marital status combined with race and other variables. Gray’s test was used to compare the cumulative incidence function of different variables. Multivariate analysis was conducted to assess prognostic factors after adjusting for other variables.

RESULTS: A total of 207,219 patients with localized prostate cancer from the SEER database from 2010 to 2016 were eligible. We found that black or single patients had the highest mortality risk (p

CONCLUSIONS: Marital status and race serve as prognostic factors for localized prostate cancer. Blacks or single people had a higher mortality risk when considered independently, and single black patients had the worst prognosis. Additionally, married status was an advantage within the same racial group, and whites and Asians had a lower risk than married and single blacks. Accordingly, the interaction between race and marital status on prostate cancer prognosis in clinical practice needs to be carefully assessed.


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